Univax-BD®

FOR ANIMAL USE ONLY

UNIVAX-BD^®
REG.NO.G3674 (Act 36/1947)
NAMIBIA REG. NO. V07/24.3/752 S0
ZIMBABWE REG. NO. 2015/80.23.17/9710

For use as an aid in the prevention of Infectious Bursal Disease (IBD / Gumboro) in chickens.

Storage instructions

• Store between and 2 ˚C and 7 ˚C in refrigerator.
• Do not freeze.
• Protect from light.

Composition
UNIVAX-BD^® is a live virus vaccine containing a mild strain (ST-12) of Infectious Bursal Disease (Gumboro) virus grown in tissue culture and combined with stabilising agents and gentamycin as preservative. The product is supplied as a lyophilised vaccine contained in vials sealed under vacuum.

Warnings

• Do not slaughter chickens for human consumption within 21 days after vaccination.
• Vaccinate healthy chickens only.
• Use only healthy embryonated eggs for the in ovo route.
• Keep out of reach of children, uninformed persons and animals.
• Do not spill or spatter the vaccine.
• Burn empty bottles, caps and all unused vaccine and accessories.
• Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

Precautions

• Use entire contents of vial when first opened.
• Wash hands thoroughly after using the vaccine.
• Do not dilute the vaccine or otherwise stretch the dosage.
• All chickens within a house should be vaccinated on the same day.
• Isolate other susceptible chickens on the premises from chickens being vaccinated.
• It is good vaccination practice to avoid contact with the eyes, hands and clothes when handling / administering the vaccine.

Directions for use
Use only as directed

When to vaccinate
Vaccinate 18 – 19 day old embryonated fowl eggs by the in ovo route using an in ovo system or subcutaneously at 1 day of age and / or by drinking water at 1 week or older. Good management practices should be followed to reduce exposure of chickens to virulent infectious bursal disease.

Preparation of the vaccine

In ovo and subcutaneous routes of administration

• Do not open and mix the vaccine until ready for use.
• Open only one vial at a time and use entire contents within 2 hours.
• Lift up top of seal on vaccine vial to expose rubber stopper. Using a sterile needle and a 5 mℓ or 10 mℓ syringe, remove a small amount (5 mℓ) of diluent from the diluent bottle and transfer this to the vaccine vial.
• Vacuum in the vaccine vial will rapidly pull in the diluent. Release the vacuum remaining in the vial.
• Vigorously shake vaccine vial with transferred diluent to rehydrate the vaccine.
• Using the same sterile needle and syringe, completely transfer the rehydrated vaccine to the remaining diluent in the diluent bottle. Rinse syringe and vaccine vial by withdrawing additional diluent and repeating the process.
• Vigorously shake final rehydrated vaccine for 20 – 30 seconds to mix thoroughly.
• The vaccine is now ready for use. 

Drinking water method.

• Assemble the vaccine and equipment needed to vaccinate the entire flock at one time.
• Do not open and mix the vaccine until ready for use.
• Remove the tear-off aluminium seal from the vaccine vial without disturbing the rubber stopper.
• Use cool, clean, non-chlorinated water as directed under “How to vaccinate”.
• Holding the vial submerged in a bucket of water or under a running stream of water, lift the lip of the rubber stopper so that the water is sucked into the vial.
• Reseal the stopper and shake the vial to thoroughly dissolve the vaccine.

How to vaccinate

1. By in ovo route of administration:
   • Consult the in ovo system operator’s manual before attempting any in ovo vaccination.
   • Sanitise the in ovo system according to the operator’s manual.
   • The in ovo system should be calibrated accurately to deliver 0,05 mℓ into each embryonated egg.
2. By subcutaneous route of administration:
   • Insert a filling tube (large, sharpened transfer tube) into the bottle of vaccine.
   • Connect the filling tube by means of rubber or plastic tubing to an automatic vaccinator fitted with a 22 gauge needle.
3. By drinking water method:     
   • Do not mix the vaccine into the drinking water until ready for use.
   • Withhold water for 1 – 2 hours depending on the ambient temperature before vaccinating so chickens are thirsty.
   • Thoroughly clean and rinse all watering containers so that no residual disinfectants remain.
   • Dilute the vaccine immediately before use with cool, clean, non­chlorinated water.
   • Pour the dissolved vaccine material into the following amounts of water and mix thoroughly.

Each 1 000 chickens:

Age	Water
1 week	6,5 litres
2 – 4 weeks	10 litres
4 – 8 weeks	20 litres
Over 8 weeks	40 litres

• Distribute diluted vaccine so that all chickens are able to drink within a 1 hour period and do not add any more water until the vaccine is consumed.
• Avoid placing water in direct sunlight.
• Use only as indicated.

Presentation
Vials containing 5 000 dose.

Registration holder:
lntervet South Africa (Pty) Ltd. Co. Reg. No. 1991/006580/07
20 Spartan Road,
Spartan, 1619
RSA
Tel: +27 (0) 11 923 9300
Fax: +27 (0) 11 392 3158
www.msd-animal-health.co.za